Vagner Gonçalves was loaned out to kryvbas kryvyi rih on a one-yr long deal. Bohdan Sarnavskyi was loaned out to kryvbas kryvyi rih on a one-yr long deal. Dnipro-1 announced that an agreement became signed with Parimatch, who will be their main sponsor. On 28 July 2021, Vladyslav Dubinchak, who played for Dnipro-1 the preceding season on loan from dynamo Kyiv, signed another 1-12 months loan deal with the team. On 19 July 2021, Mario Ćuže, who played for Dnipro-1 inside the 2d part of the previous season on a mortgage from Dinamo Zagreb, signed y another 1-year loan deal with the team. On the same day, the club presented its new kit for the season.

The home kit is navy blue with blue sleeves. Goalkeeper kits are green, yellow, and sky blue. On 5 July 2021, Valentin Cojocaru was signed for €100,000 from Viitorul Constanța, with the Romanian goalkeeper signing a 2-year contract. On the same day, even past became signed on a free transfer after his contract with Desna Chernihiv expired, with the player signing a 2-year contract. On 30 June 2021, Nazariy Rusyn was signed on a one-12 months loan deal from dynamo Kyiv, with the player joining the club on 1 July once the summertime transfer window opens. On 25 June 2021, Andriy Tsurikov signed on a free transfer for Metalist Kharkiv, with the player joining the brand new club on 1 July after his contract expired.

On 25 June 2021, Oleksandr Pikhalyonok, who performed the preceding 12 months on loan from Shakhtar Donetsk, signed a 4-year contract with the team from Dnipro, with the transfer being valued at €700,000. Oleksandr Safronov joined Desna Chernihiv, slot gacor Zauri Makharadze joined Polissya Zhytomyr, Douglas joined Giresunspor, and Lucas Taylor joined PAOK. On 23 July 2021, Oleksandr Byelyayev was loaned out to Gençlerbirliği on a one-year long deal. On 30 June 2021, four players left the club after their contracts expired. On 12 July 2021, Mykyta Kravchenko was signed on a one-year loan deal from Dynamo Kyiv. For the first time in its four-year records, Dnipro-1 will have the brand of a sponsor proven on the front of the shirt. Shandi Ren Finnessey, born June 9, 1978, is an American actress, model, TV host, and splendor queen.